Evaluation of xanthine oxidase inhibitory, antioxidative activity of five selected Papua medicinal plants and correlation with phytochemical content

نویسندگان

چکیده

Some medicinal plants from Papua have been used traditionally as hyperuricemia and antioxidant agents for many ethnic in Islands. The present study aims to evaluate inhibitory xanthine oxidase, antioxidative activities, total phenolic, flavonoid of five selected plants, Myrmecodia beccarii , Villebrunea rubescens Breynia cernua Bridelia spp. Dodonaea viscosa . Preliminary phytochemical screening revealed the presence flavonoids phenolic compounds with TLC-densitometric analysis, which is responsible biological activities different plant extracts. Antioxidant was tested by 2,2- diphenyl-1- picrylhydrazyl (DPPH) cupric ion capacity (CUPRAC) methods expressed Activity Index (AAI). Xanthine oxidase (XOI) activity evaluated a spectrophotometer. ethyl acetate extract (MEA) showed highest XOI activity. MEA may be developed new potential source agent.

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ژورنال

عنوان ژورنال: ????????

سال: 2022

ISSN: ['2411-6076', '2709-135X']

DOI: https://doi.org/10.3897/pharmacia.69.e91083